Pragmatism in clinical trials aims to enhance the applicability of research findings in everyday clinical settings. Hybridism in clinical trials, which involves evaluating both clinical effectiveness and implementation success, seeks to accelerate the development and adoption of evidence-based practices in routine clinical care.
While pragmatic trial methodologies and implementation science originated from distinct disciplines, Pragmatic Trials and Hybrid Effectiveness-Implementation Trials exhibit numerous overlapping design characteristics. Consequently, there is a risk of confusion between these trial types, leading investigators to misidentify their trial or utilize an inappropriate trial design to address their research query.
This webinar aims to provide clear explanations of the similarities and differences between these trial types. Additionally, it will offer practical recommendations to assist investigators in selecting, labelling, and implementing the most suitable trial type for addressing their research question. These recommendations serve as valuable additions to the existing reporting guidelines for clinical effectiveness trials (TIDieR) and implementation trials (StaRI).
Speakers: Professor Geoffrey M. Curran, PhD
Endowed Chair in Pharmacy Practice Innovation
Professor, Departments of Pharmacy Practice and Psychiatry
Director, Center for Implementation Research
University of Arkansas for Medical Sciences
Adjunct Professor, Department of Nursing and Midwifery
University of Limerick, Ireland
Prof. John C. Fortney
Department of Psychiatry and Behavioural Sciences
University of Washington School of Medicine
