Welcome to the HRB Trials Methodology Research Network
The HRB-Trials Methodology Research Network (HRB-TMRN) is a collaborative initiative between a number of Irish and international higher education institutes and methodology centers.
The David L. Sackett Young Investigator Award recognizes exceptional early-career researchers who exemplify the values of creativity, scientific excellence, and impactful contributions
Trials Methodology Funding Success: University of Limerick Secures Funding to Develop Core Outcome Set for Comprehensive Geriatric Assessment. Health Research Board –
The HRB-TMRN is a proud Partner in the MRC-NIHR-Trials Methodology Research Partnership in the UK. This Partnership offers significant opportunity for trials
The HRB-Trials Methodology Research Network (HRB-TMRN) is a collaborative initiative between several Irish and international higher education institutes and methodology centres.
We want to strengthen the methodology and reporting of trials in health and social care in Ireland so that they become more relevant, accessible and influential for our community of patients and other service users, practitioners, policymakers and the public. This is achieved through a programme of work relating to the methodology of trials and focused on (i) support, (ii) training and education, (iii) research and innovation and (iv) Public and Patient Involvement and Engagement.
Help our colleagues reduce the #carbonfootprint of #clinicaltrials! 🌍 @MRCNIHRTMRP are conducting a survey to explore trialists' views on factors influencing greener trial practices.
Our Network is connected to over 70 national and international trials and trials methodology organisations. We are a partner within the MRC-NIHR-Trials Methodology Research Partnership in the UK. Our collaborations give us access to world leaders in trials methodology research.
Our trials methodology research expertise includes:
Studies within a
Trial (SWAT)
A SWAT is an embedded methodology research study within a planned or ongoing trial. We have been involved in SWATS for over 10 years and were involved in the first registered SWAT and we provide annual competitive funding for SWATs. Our members are active in developing and implementing SWATs across a variety of clinical trials nationally and internationally.
Core Outcome
Set Development
A core outcome set is agreed, standardised set of outcomes that should be measured and reported in all trials for a specific clinical area. We have been involved in developing core outcome sets across a range of clinical areas. We are proud to collaborate with the COMET Initiative in many of these.
Priority
Setting
Priority Setting Partnerships (PSPs) enable clinicians, patients and carers to work together to identify and prioritise evidence uncertainties in particular areas of health and care that could be answered by research.We have led or contributed to research agenda setting across a range of trials methodology topics and also promoted the use of prioritisation setting across clinical trial areas nationally.
Qualitative Research in Trials Methodology
We have specialized expertise in qualitative research in our Qualitative Research in Trials Centre (@QUESTSCentre). Here a team of advisors with expertise in case study research, ethnography, grounded theory, phenomenology and qualitative evidence synthesis are active in a wide range of trials methodology projects.
This event will require a fully refundable registration deposit of €20. This is so we can reduce waste and cover unnecessary costs. Attendees will be refunded on arrival through Eventbrite. Please note: Refunds on Eventbrite typically take 5 to 7 business days to process.
This free in-person workshop focuses on innovative designs for trials with complex interventions. The event will start with a lunch from 12pm, follow by talks from experts in the area, and
Event Details
This free in-person workshop focuses on innovative designs for trials with complex interventions. The event will start with a lunch from 12pm, follow by talks from experts in the area, and end with a panel discussion/ Q&A session. Topics include simulation study planning, methodology challenges and experience on running/ applying trial grants. A detailed programme will be circulated to participants in due course.
No preliminary knowledge on adaptive designs and other complex trial designs are expected.
Target audience: Trial statisticians working in CTU in the United Kingdom of Great Britain and Ireland. Early and mid-career statisticians are strongly encouraged to attend. In the event that there is a large number of attendees from the same institution, a selection process will take place by the organisers.
Date & time: Wednesday 12th March 2025, 12pm-5pm
Venue: King’s College London, Waterloo Campus
Cost: Free. This event is supported by the MRC-NIHR Trials Methodology Research Partnership (TMRP).
Registration is now open – CLICK HERE
This one day in-person conference will bring together world leading researchers, patient advocates, industry representatives and other stakeholders to share
This one day in-person conference will bring together world leading researchers, patient advocates, industry representatives and other stakeholders to share knowledge and lived experience across topics such as rare disease research methodology, translation, European Reference Network Patient Registries and rare disease clinical trial partner perspectives.
Rare disease researchers and clinical trialists will be able to showcase their work through poster presentations. Submission of abstracts of rare disease case studies and research are now invited and the deadline is Friday 7th February 2025. Please click hereto view the abstract call.
The O’Reilly Hall, UCD is a wheelchair accessible venue. If you wish to discuss any accessibility requirements, please email RDCTN@ucd.ie.
We are a Health Research Board (HRB) – funded network aiming to increase activity in rare disease clinical trials in Ireland. Through collaboration with patients, researchers and industry, we support development of rare disease clinical trials, trial methodology and researcher training, while keeping the patient voice at the centre of everything we do.
Rethinking Clinical Trials: Inclusivity in Practice
ECRIN are delighted to announce International Clinical Trials Day (ICTD) 2025 | Rethinking Clinical Trials: Inclusivity in Practice,
Event Details
Rethinking Clinical Trials: Inclusivity in Practice
ECRIN are delighted to announce International Clinical Trials Day (ICTD) 2025 | Rethinking Clinical Trials: Inclusivity in Practice, co-hosted by ECRIN and SCReN in Madrid. It will take place on Tuesday, May 20, 2025.
Launched in 2005 by ECRIN, in line with its mission to support multinational clinical research in Europe, ICTD brings together patients, health policy actors, health authorities, clinical researchers, health professionals and citizens from Europe, and beyond to discuss issues related to multinational clinical studies. ICTD commemorates the start of the landmark clinical trial, led by James Lind on sailors with scurvy, 20 May 1747. Having laid the foundation for modern clinical research, ECRIN salutes this initiative by addressing a new topic in clinical research every year on or around this date.
The need for greater inclusivity in clinical trials is clear in Europe and there is an increasing obligation to progress from discussion to concrete implementation. By uniting different stakeholders from the community, ICTD will shed light not only on why diversity, equity and inclusion should be embraced in clinical research but will give concrete examples of what has been done so far and where there are still hurdles to overcome.
ECRIN, the European Clinical Research Infrastructure Network, facilitates multinational clinical research, through the provision of advice and services for the set-up and management of investigator or SME led clinical studies in Europe. ECRIN unites national networks of clinical trial units across Europe, through its scientific partners, to fulfil its vision of generating scientific evidence to optimise medical practice.
More details available soon. https://www.universityofgalway.ie/instituteforclinicaltrials/education/
Led by the Institute for Clinical Trials, University of Galway.
We work collaboratively and innovatively. Our doors are always open to new ideas in Trials methodology.
Inclusion
Involvement of all key stakeholders including patients and the public is central to what we do. This helps us ensure our work will matter most and achieve impact.
Capacity
Capacity-building is central to all our work. This is essential to provide opportunity, invigorate perspective and build our research future.
Our Network operates across five University Partners, each leading the way in trials methodology research and training